Publications

recently in press

A microbial metabolite synergizes with endogenous serotonin to trigger C. elegans reproductive behavior

WormBase author report for Ringstad (includes Worm Meeting abstracts)

Choi JH, Horowitz LB and Ringstad N. Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit. (2021) Nat Commun. 12, 6334 Pubmed Nat Commun PMC Article

Rossillo M and Ringstad N. Development of specialized sensory neurons engages a nuclear receptor required for functional plasticity. (2020) Genes Dev. 34, 1666-1679 Pubmed Genes Dev PMC Article

Chen YC, Seyedsayamdost MR and Ringstad N. A microbial metabolite synergizes with endogenous serotonin to trigger reproductive behavior. (2020) Proc Natl Acad Sci U S A. 117, 30589-30598 Pubmed Proc Natl Acad Sci U S A PMC Article

Brissette B and Ringstad N. Insulin-like Peptides as Agents of Social Change. (2019) Neuron. 104, 1027-1028 Pubmed Neuron

Horowitz LB, Brandt JP and Ringstad N. Repression of an activity-dependent autocrine insulin signal is required for sensory neuron development in . (2019) Development. 146, Pubmed Development PMC Article

Aydin B, Kakumanu A, Rossillo M, Moreno-Estellés M, Garipler G, Ringstad N, Flames N, Mahony S and Mazzoni EO. Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes. (2019) Nat Neurosci. 22, 897-908 Pubmed Nat Neurosci PMC Article

Brandt JP, Rossillo M, Du Z, Ichikawa D, Barnes K, Chen A, Noyes M, Bao Z and Ringstad N. Lineage context switches the function of a Pax6 homolog in determining a neuronal fate. (2019) Development. 146, Pubmed Development PMC Article

Van Bael S, Watteyne J, Boonen K, De Haes W, Menschaert G, Ringstad N, Horvitz HR, Schoofs L, Husson SJ and Temmerman L. Mass spectrometric evidence for neuropeptide-amidating enzymes in . (2018) J Biol Chem. 293, 6052-6063 Pubmed J Biol Chem PMC Article

Martínez-Velázquez LA and Ringstad N. Antagonistic regulation of trafficking to sensory cilia by a homolog and retromer. (2018) Proc Natl Acad Sci U S A. 115, E438-E447 Pubmed Proc Natl Acad Sci U S A PMC Article

Ringstad N. Neuromodulation: The Fevered Mind of the Worm. (2017) Curr Biol. 27, R315-R317 Pubmed Curr Biol

Zang KE, Ho E and Ringstad N. Inhibitory peptidergic modulation of serotonin neurons is gated by T-type calcium channels. (2017) Elife. 6, Pubmed Elife PMC Article

Ringstad N. A Controlled Burn: Sensing Oxygen to Tune Fat Metabolism. (2016) Cell Rep. 14, 1569-1570 Pubmed Cell Rep

Brandt JP and Ringstad N. Toll-like Receptor Signaling Promotes Development and Function of Sensory Neurons Required for a C. elegans Pathogen-Avoidance Behavior. (2015) Curr Biol. 25, 2228-37 Pubmed Curr Biol PMC Article

Kim S, Lee K, Choi JH, Ringstad N and Dynlacht BD. Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle. (2015) Nat Commun. 6, 8087 Pubmed Nat Commun PMC Article

Ringstad N. Fatal attraction. (2014) Elife. 3, Pubmed Elife PMC Article

Smith ES, Martinez-Velazquez L and Ringstad N. A chemoreceptor that detects molecular carbon dioxide. (2013) J Biol Chem. 288, 37071-81 Pubmed J Biol Chem PMC Article

Emtage L, Aziz-Zaman S, Padovan-Merhar O, Horvitz HR, Fang-Yen C and Ringstad N. IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a G(o) signaling pathway. (2012) J Neurosci. 32, 16285-95 Pubmed J Neurosci PMC Article

Ma DK and Ringstad N. The neurobiology of sensing respiratory gases for the control of animal behavior. (2012) Front Biol (Beijing). 7, 246-253 Pubmed Front Biol (Beijing) PMC Article

Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM, Horvitz HR, Sternberg PW and Ringstad N. Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans. (2011) Proc Natl Acad Sci U S A. 108, 254-9 Pubmed Proc Natl Acad Sci U S A PMC Article

Ringstad N, Abe N and Horvitz HR. Ligand-gated chloride channels are receptors for biogenic amines in C. elegans. (2009) Science. 325, 96-100 Pubmed Science PMC Article

Ringstad N and Horvitz HR. FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans. (2008) Nat Neurosci. 11, 1168-76 Pubmed Nat Neurosci PMC Article

Alkema MJ, Hunter-Ensor M, Ringstad N and Horvitz HR. Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system. (2005) Neuron. 46, 247-60 Pubmed Neuron

Nemoto Y, Wenk MR, Watanabe M, Daniell L, Murakami T, Ringstad N, Yamada H, Takei K and De Camilli P. Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals. (2001) J Biol Chem. 276, 41133-42 Pubmed J Biol Chem

Ringstad N, Nemoto Y and De Camilli P. Differential expression of endophilin 1 and 2 dimers at central nervous system synapses. (2001) J Biol Chem. 276, 40424-30 Pubmed J Biol Chem

Farsad K, Ringstad N, Takei K, Floyd SR, Rose K and De Camilli P. Generation of high curvature membranes mediated by direct endophilin bilayer interactions. (2001) J Cell Biol. 155, 193-200 Pubmed J Cell Biol PMC Article

Gad H, Ringstad N, Löw P, Kjaerulff O, Gustafsson J, Wenk M, Di Paolo G, Nemoto Y, Crun J, Ellisman MH, De Camilli P, Shupliakov O and Brodin L. Fission and uncoating of synaptic clathrin-coated vesicles are perturbed by disruption of interactions with the SH3 domain of endophilin. (2000) Neuron. 27, 301-12 Pubmed Neuron

Ochoa GC, Slepnev VI, Neff L, Ringstad N, Takei K, Daniell L, Kim W, Cao H, McNiven M, Baron R and De Camilli P. A functional link between dynamin and the actin cytoskeleton at podosomes. (2000) J Cell Biol. 150, 377-89 Pubmed J Cell Biol PMC Article

Tang Y, Hu LA, Miller WE, Ringstad N, Hall RA, Pitcher JA, DeCamilli P and Lefkowitz RJ. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. (1999) Proc Natl Acad Sci U S A. 96, 12559-64 Pubmed Proc Natl Acad Sci U S A PMC Article

Ringstad N, Gad H, Löw P, Di Paolo G, Brodin L, Shupliakov O and De Camilli P. Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis. (1999) Neuron. 24, 143-54 Pubmed Neuron

Haffner C, Takei K, Chen H, Ringstad N, Hudson A, Butler MH, Salcini AE, Di Fiore PP and De Camilli P. Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15. (1997) FEBS Lett. 419, 175-80 Pubmed FEBS Lett

Ringstad N, Nemoto Y and De Camilli P. The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. (1997) Proc Natl Acad Sci U S A. 94, 8569-74 Pubmed Proc Natl Acad Sci U S A PMC Article

Ariza RR, Li Z, Ringstad N and Demple B. Activation of multiple antibiotic resistance and binding of stress-inducible promoters by Escherichia coli Rob protein. (1995) J Bacteriol. 177, 1655-61 Pubmed J Bacteriol PMC Article

Brandt JP, Aziz-Zaman S, Juozaityte V, Martinez-Velazquez LA, Petersen JG, Pocock R and Ringstad N. A single gene target of an ETS-family transcription factor determines neuronal CO2-chemosensitivity. (2012) PLoS One. 7, e34014 Pubmed PLoS One PMC Article

Choi JH, Horowitz LB and Ringstad N. Opponent vesicular transporters regulate the strength of glutamatergic neurotransmission in a C. elegans sensory circuit.

(2021) Nat Commun. 12, 6334

Pubmed Nat Commun PMC Article

Rossillo M and Ringstad N.
Development of specialized sensory neurons engages a nuclear receptor required for functional plasticity.
(2020) Genes Dev. 34, 1666-1679

Pubmed

Genes Dev

PMC Article

Chen YC, Seyedsayamdost MR and Ringstad N.
A microbial metabolite synergizes with endogenous serotonin to trigger reproductive behavior.
(2020) Proc Natl Acad Sci U S A. 117, 30589-30598

Pubmed

Proc Natl Acad Sci U S A

PMC Article

Brissette B and Ringstad N.
Insulin-like Peptides as Agents of Social Change.
(2019) Neuron. 104, 1027-1028

Pubmed

Neuron

Horowitz LB, Brandt JP and Ringstad N.
Repression of an activity-dependent autocrine insulin signal is required for sensory neuron development in .
(2019) Development. 146,

Pubmed

Development

PMC Article

Aydin B, Kakumanu A, Rossillo M, Moreno-Estellés M, Garipler G, Ringstad N, Flames N, Mahony S and Mazzoni EO.
Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes.
(2019) Nat Neurosci. 22, 897-908

Pubmed

Nat Neurosci

PMC Article

Brandt JP, Rossillo M, Du Z, Ichikawa D, Barnes K, Chen A, Noyes M, Bao Z and Ringstad N.
Lineage context switches the function of a Pax6 homolog in determining a neuronal fate.
(2019) Development. 146,

Pubmed

Development

PMC Article

Van Bael S, Watteyne J, Boonen K, De Haes W, Menschaert G, Ringstad N, Horvitz HR, Schoofs L, Husson SJ and Temmerman L.
Mass spectrometric evidence for neuropeptide-amidating enzymes in .
(2018) J Biol Chem. 293, 6052-6063

Pubmed

J Biol Chem

PMC Article

Martínez-Velázquez LA and Ringstad N.
Antagonistic regulation of trafficking to sensory cilia by a homolog and retromer.
(2018) Proc Natl Acad Sci U S A. 115, E438-E447

Pubmed

Proc Natl Acad Sci U S A

PMC Article

Ringstad N.
Neuromodulation: The Fevered Mind of the Worm.
(2017) Curr Biol. 27, R315-R317

Pubmed

Curr Biol

Zang KE, Ho E and Ringstad N.
Inhibitory peptidergic modulation of serotonin neurons is gated by T-type calcium channels.
(2017) Elife. 6,

Pubmed

Elife

PMC Article

Ringstad N.
A Controlled Burn: Sensing Oxygen to Tune Fat Metabolism.
(2016) Cell Rep. 14, 1569-1570

Pubmed

Cell Rep

Brandt JP and Ringstad N.
Toll-like Receptor Signaling Promotes Development and Function of Sensory Neurons Required for a C. elegans Pathogen-Avoidance Behavior.
(2015) Curr Biol. 25, 2228-37

Pubmed

Curr Biol

PMC Article

Kim S, Lee K, Choi JH, Ringstad N and Dynlacht BD.
Nek2 activation of Kif24 ensures cilium disassembly during the cell cycle.
(2015) Nat Commun. 6, 8087

Pubmed

Nat Commun

PMC Article

Ringstad N.
Fatal attraction.
(2014) Elife. 3,

Pubmed

Elife

PMC Article

Smith ES, Martinez-Velazquez L and Ringstad N.
A chemoreceptor that detects molecular carbon dioxide.
(2013) J Biol Chem. 288, 37071-81

Pubmed

J Biol Chem

PMC Article

Emtage L, Aziz-Zaman S, Padovan-Merhar O, Horvitz HR, Fang-Yen C and Ringstad N.
IRK-1 potassium channels mediate peptidergic inhibition of Caenorhabditis elegans serotonin neurons via a G(o) signaling pathway.
(2012) J Neurosci. 32, 16285-95

Pubmed

J Neurosci

PMC Article

Ma DK and Ringstad N.
The neurobiology of sensing respiratory gases for the control of animal behavior.
(2012) Front Biol (Beijing). 7, 246-253

Pubmed

Front Biol (Beijing)

PMC Article

Brandt JP, Aziz-Zaman S, Juozaityte V, Martinez-Velazquez LA, Petersen JG, Pocock R and Ringstad N.
A single gene target of an ETS-family transcription factor determines neuronal CO2-chemosensitivity.
(2012) PLoS One. 7, e34014

Pubmed

PLoS One

PMC Article

Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM, Horvitz HR, Sternberg PW and Ringstad N.
Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans.
(2011) Proc Natl Acad Sci U S A. 108, 254-9

Pubmed

Proc Natl Acad Sci U S A

PMC Article

Ringstad N, Abe N and Horvitz HR.
Ligand-gated chloride channels are receptors for biogenic amines in C. elegans.
(2009) Science. 325, 96-100

Pubmed

Science

PMC Article

Ringstad N and Horvitz HR.
FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans.
(2008) Nat Neurosci. 11, 1168-76

Pubmed

Nat Neurosci

PMC Article

Alkema MJ, Hunter-Ensor M, Ringstad N and Horvitz HR.
Tyramine Functions independently of octopamine in the Caenorhabditis elegans nervous system.
(2005) Neuron. 46, 247-60

Pubmed

Neuron

Nemoto Y, Wenk MR, Watanabe M, Daniell L, Murakami T, Ringstad N, Yamada H, Takei K and De Camilli P.
Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals.
(2001) J Biol Chem. 276, 41133-42

Pubmed

J Biol Chem

Ringstad N, Nemoto Y and De Camilli P.
Differential expression of endophilin 1 and 2 dimers at central nervous system synapses.
(2001) J Biol Chem. 276, 40424-30

Pubmed

J Biol Chem

Farsad K, Ringstad N, Takei K, Floyd SR, Rose K and De Camilli P.
Generation of high curvature membranes mediated by direct endophilin bilayer interactions.
(2001) J Cell Biol. 155, 193-200

Pubmed

J Cell Biol

PMC Article

Gad H, Ringstad N, Löw P, Kjaerulff O, Gustafsson J, Wenk M, Di Paolo G, Nemoto Y, Crun J, Ellisman MH, De Camilli P, Shupliakov O and Brodin L.
Fission and uncoating of synaptic clathrin-coated vesicles are perturbed by disruption of interactions with the SH3 domain of endophilin.
(2000) Neuron. 27, 301-12

Pubmed

Neuron

Ochoa GC, Slepnev VI, Neff L, Ringstad N, Takei K, Daniell L, Kim W, Cao H, McNiven M, Baron R and De Camilli P.
A functional link between dynamin and the actin cytoskeleton at podosomes.
(2000) J Cell Biol. 150, 377-89

Pubmed

J Cell Biol

PMC Article

Tang Y, Hu LA, Miller WE, Ringstad N, Hall RA, Pitcher JA, DeCamilli P and Lefkowitz RJ.
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor.
(1999) Proc Natl Acad Sci U S A. 96, 12559-64

Pubmed

Proc Natl Acad Sci U S A

PMC Article

Ringstad N, Gad H, Löw P, Di Paolo G, Brodin L, Shupliakov O and De Camilli P.
Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis.
(1999) Neuron. 24, 143-54

Pubmed

Neuron

Haffner C, Takei K, Chen H, Ringstad N, Hudson A, Butler MH, Salcini AE, Di Fiore PP and De Camilli P.
Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15.
(1997) FEBS Lett. 419, 175-80

Pubmed

FEBS Lett

Ringstad N, Nemoto Y and De Camilli P.
The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.
(1997) Proc Natl Acad Sci U S A. 94, 8569-74

Pubmed

Proc Natl Acad Sci U S A

PMC Article

Ariza RR, Li Z, Ringstad N and Demple B.
Activation of multiple antibiotic resistance and binding of stress-inducible promoters by Escherichia coli Rob protein.
(1995) J Bacteriol. 177, 1655-61

Pubmed

J Bacteriol

PMC Article